Karachi administrator Saif Ur Rehman said, "Since yesterday, the elephant has been ill with a fever." The elephant had been dealing with many health concerns for the past few days, and she had received "all-out efforts" to save her.
Noor Jehan's final days were spent being constantly drenched in water to keep her cool and pin-pricked by drops.
As he expressed grief at Noor Jehan's passing, the administrator mentioned that Four Paws International treated the 17-year-old recently.
While talking to journalists, Karachi Zoo Director Kanwar Ayub said the elephant's health had been declining since November of last year. The elephant passed away at 11:15 this morning, he added.
The director of the zoo noted that the Four Paws team was traveling to Pakistan and would examine the body of the 17-year-old after her death.
He thanked the Four Paws team for their efforts in caring for the elephant and said, "After the post-mortem examination, we will decide about her burial."
Noor Jehan had surgery a few months ago, and the zoo's administration said that following the most recent procedure, she had trouble walking.
The administration said, "A few days ago, Noor Jehan sat down in the pond but was unable to stand up again."
The African elephant, who was 17 years old, underwent emergency surgery for a tumor on April 5 in Karachi but eventually collapsed and has been lying on its side ever since.
Animal rights advocates from Pakistan and beyond publicized Noor Jehan's tragic suffering on social media, sparking demands for the closure of the zoo.
A court ordered the sole facility in the country's capital to close in 2020 due to its dilapidated condition since Pakistan's zoos are routinely accused of disrespecting animal welfare.
2019 saw the closure of Islamabad's zoo after it received widespread criticism for how it handled an Asian elephant by the name of "Kaavan."
Later, "Kavaan" was transported to Cambodia as part of a project led by US singer and actor Cher and completed by Four Paws.